Dr Frassetto: Unique Opportunity to Drive Paleo Diet Study v. ADA Whole Wheat/Gluten 'Healthy Diet' for PCOS

Allan and his family reported their self monitored blood glucoses here. AmGut results soon as it takes about half a year.




UCSF Paleo Diet v ADA Whole Wheat Healthy Diet for PCOS

At UCSF Dr Lynda Frassetto et al are requesting help to prove the value and merit of the paleo diet for insulin resistant states such as PCOS. She is working collaboratively with other researchers to obtain funding for the next landmark study. What they collect via Crowdfund can be retained even if they do not reach the $40,000 goal. Dr Frassetto and I believe the paleo diet offers many hormonal and cognitive/behavioral benefits for those with insulin resistant states. I've spoken with Dr Frassetto to promote the diet at an EBT conference for emotional behavior therapy (Wired for Joy) because their participants see great mental and brain changes that complement the program.

What is needed is well designed and articulated studies like her earlier, seminal Paleo study that showed dramatic normalization of blood pressures in pre-hypertensive adults. This was not a low carb study but a basic, no grains, no legumes, no dairy paleo diet including some tubers (carrots, yams, etc). Her goal is to prove health benefits again for a group of patients that have few medical options (metformin, starvation weight loss diets, IVF, fertility treatment, etc). As you are aware in the paleosphere, many cases of spontaneous fertility and resolution of PCOS are commonplace.

A few days ago, they opened their UCSF-Crowdfund account and received $2855 already. Government funding has become scarcer of late. Many of the medical personnel for this study are in fact all volunteering their time according to Dr Frassetto. Unlike the prior study, outpatient food is not provided. Nutri Sci students (like I used to be LOL) from UC Berkeley will be volunteering to counsel diet information to trial participants. Costs for Free-testosterone, insulin, and other lab hormone measurements will be covered by funds collected.

Polycystic ovary syndrome (PCOS) is a syndrome which includes elevated androgen levels, irregular menstrual cycles and insulin resistance. Standard treatments, which include weight loss and medications to improve insulin secretion are only partly successful, and may require that young women take medications for decades.
The study investigators have been evaluating the effects of specific diets on insulin resistance in healthy volunteers and subjects with type 2 diabetes, and have found that subjects with insulin resistance seem to respond particularly well to these diet regimens.
Volunteers with PCOS are being asked to participate to see if following these diets can help regularize your menstrual cycles. The results of this study may help improve fertility treatments for women with PCOS.

An incentive from UCSF has thrown in:

Special early-bird incentive: Meet us at the Ancestral Health Symposium

Dr. Lynda Frassetto and Dr. Ashley Mason will be attending the Ancestral Health Symposium in Berkeley, CA August 7-9. We'd be happy to meet with you and talk about the study -- or if you donate at the $250 level, we'll take you to lunch and talk about anything you want!

Project Details ~~  http://clinicaltrials.gov/ct2/show/NCT02190097

How we'll spend the money

All $40,000 will go to costs for the study – the study personnel are all volunteering their time! Here's our approximate budget:

$20,000: Laboratory tests of insulin resistance and other biological outcomes.
$12,000: Research supplies and lab space.
$4000: Payments to participants for providing questionnaires, urine and blood samples, and uterine images.
$4000: Tracking and staying in touch with participants, data entry and administrative support.

Stephan G. at Whole Health also shares his thoughts: HERE

Thank you for your support!